Construction and evaluation of a switch‐tuned ¹³C ‐ ¹H birdcage radiofrequency coil for imaging the metabolism of hyperpolarized ¹³C‐enriched compounds

Abstract

A surface coil can be integrated with a switch-tuned (13) C - (1) H coil for (13) C TORO operation producing improved SNR. In vivo metabolic imaging of [1-(13) C]pyruvate in a rat model of glioma is demonstrated using TORO operation, which is co-registered with (1) H-imaged anatomy.