PRELIMINARY EXPERIENCES WITH TRANSPLANTS OF CULTURED PARATHYROID TISSUE IN HYPOPARATHYROIDISM

Abstract

Article1 April 1957PRELIMINARY EXPERIENCES WITH TRANSPLANTS OF CULTURED PARATHYROID TISSUE IN HYPOPARATHYROIDISMROBERTO F. ESCAMILLA, M.D., F.A.C.P., C. HENRY KEMPE, M.D., JACKSON CRANE, M.D., LEON GOLDMAN, M.D., F.A.C.S., GILBERT S. GORDAN, M.D., F.A.C.P.ROBERTO F. ESCAMILLA, M.D., F.A.C.P.Search for more papers by this author, C. HENRY KEMPE, M.D.Search for more papers by this author, JACKSON CRANE, M.D.Search for more papers by this author, LEON GOLDMAN, M.D., F.A.C.S.Search for more papers by this author, GILBERT S. GORDAN, M.D., F.A.C.P.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-46-4-649 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptA number of attempts to transplant parathyroid tissue into patients with hypoparathyroidism have been made in the past. Results have not been consistent, although occasional isolated successes have been reported. In a review of the problem in 1933, Stone, Owings and Gey1mentioned tissue culture adaptation with host serum as a possible solution, and expressed the hope that many endocrine deficiencies might be treated by grafts of living tissue. More recently, Gaillard,2-4crediting Gassul5and Erdmann6with the idea of attempting to "adapt" explants to the humoral milieu of the future host in tissue culture, reported the results of transplants...Bibliography1. StoneOwingsGey HBJCGO: Living grafts of endocrine glands, California and West. Med. 38: 409-411 (June) 1933; 39: 10-12 (July) 1933; 39: 81-83 (Aug.) 1933. MedlineGoogle Scholar2. Gaillard PJ: Growth and differentiation of explanted tissue, Internat. Rev. Cytology 2: 341-402, 1953. Google Scholar3. Gaillard PJ: Transplantation of cultivated parathyroid gland tissue in man, in Ciba Foundation Symposium, "Preservation and transplantation of normal tissues," G. E. W. Wolstenholme and M. P. Cameron, Editors, 1954, Little, Brown and Co., Boston, pp. 100-109. CrossrefGoogle Scholar4. Gaillard PJ: Die Transplantation von gezuchtetem Gewebe und das Alter des Empfängers, Schweiz. med. Wchnschr. 85: 846-847 (Aug. 27) 1955. MedlineGoogle Scholar5. Gassul R: Experimentelle Studien ueber Auspflanzung, Ueberpflanzung, und Regeneration von Explantaten aus erwachsener Froschhaut, Arch. f. Entwcklngsmechn. d. Organ. 52: 400-446, 1922-23. Google Scholar6. Erdmann R: Verwandtschaftsbeziehungen der Anurenfamilien geprüft durch Implantationsversuche gezüchteter Haut, Arch. f. Entwcklngsmechn. d. Organ. 112: 739-806 (Nov. 15) 1927. CrossrefGoogle Scholar7. SterlingGoldsmith JAR: Transplantation of homologous thyroid and parathyroid glands (case report), Tr. Am. Goiter A. 477-863, 1954. Google Scholar8. BlohmWurlGillespieEscamilla RWOAJORF: Refractoriness to antitetanic therapy in a case of surgical hypoparathyroidism, J. Clin. Endocrinol. and Metabolism 13: 519-533 (May) 1953. CrossrefGoogle Scholar9. Brown JB: Homografting of skin, with report of success in identical twins, Surgery 1: 558-563, 1937. Google Scholar10. GoodVarco RARL: Successful homograft of skin in a child with agammaglobulinemia, J. A. M. A. 157: 713-716 (Feb. 26) 1955. CrossrefMedlineGoogle Scholar11. MerrillMurrayHarrisonGuild JPJEJHWR: Successful homotransplantation of the human kidney between identical twins, J. A. M. A. 160: 277-282 (Jan. 28) 1956. CrossrefMedlineGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: San Francisco, California*Presented at the Thirty-seventh Annual Session of The American College of Physicians, Los Angeles, California, April 17, 1956.From the Departments of Medicine, Pathology, Pediatrics and Surgery, University of California School of Medicine, San Francisco, California.Requests for reprints should be addressed to Roberto F. Escamilla, M.D., 384 Post Street, San Francisco 8, California. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byThe morbidity of subtotal thyroidectomyFactors influencing parathyroid allotransplantation in ratsEffects of 131I on vascularized allografts of canine thyroid and parathyroid�ber das Wachstum der Pankreaszellen von S�ugetieren als Monolayer Cultures“Successful” parathyroid transplantationMaintenance of Parathyroid Tissue Fragments on Agar SubstratesAortic-Pedicle Technic for Obtaining Immediate Vascularization of Fetal Parathyroid-Gland Transplants in ManTransplantation of tissuesCOMPARATIVE IMMUNOLOGY AND THE PHYLOGENY OF HOMOTRANSPLANTATIONENDOCRINE TRANSPLANTATIONDISABILITY 1 April 1957Volume 46, Issue 4Page: 649-661KeywordsAdenomasForecastingHypoparathyroidismParathyroidPediatric surgeryPediatricsPhosphorusResearch laboratoriesTissue culturesTransplantation ePublished: 1 December 2008 Issue Published: 1 April 1957 Copyright & PermissionsCopyright ©, 1957, by The American College of PhysiciansPDF downloadLoading ...