Identification of Soluble 14‐3‐3∊ as a Novel Subchondral Bone Mediator Involved in Cartilage Degradation in Osteoarthritis

Abstract

The results of this study identify s14-3-3∊ as a novel soluble mediator critical in the communication between subchondral bone and cartilage in OA. Thus, s14-3-3∊ may be a potential target for future therapeutic or prognostic applications in OA.