Concepedia

Phase 2 trial of linifanib (ABT‐869) in patients with unresectable or metastatic hepatocellular carcinoma

Han Chong Toh, Pei‐Jer Chen, Brian I. Carr, Jennifer J. Knox, Sharlene Gill, Peter Ansell, Evelyn McKeegan, Barry L. Dowell, Michelle Pedersen, Qin Qin,

Cancer · 2012 · 106 citations · 33 references

DOIFull text

Open access

Abstract

Single-agent linifanib was found to be clinically active in patients with advanced hepatocellular carcinoma, with an acceptable safety profile.

References

33

New Guidelines to Evaluate the Response to Treatment in Solid Tumors

Patrick Therasse, Susan G. Arbuck, Elizabeth A. Eisenhauer et al. · JNCI Journal of the National Cancer Institute · 2000 · 15.7K citations

, , +17

Sorafenib in Advanced Hepatocellular Carcinoma

Josep M. Llovet, Sergio Ricci, Vincenzo Mazzaferro et al. · New England Journal of Medicine · 2008 · 12.8K citations · Full text

Efficacy and safety of sorafenib in patients in the Asia-Pacific region with advanced hepatocellular carcinoma: a phase III randomised, double-blind, placebo-controlled trial

Ann‐Lii Cheng, Yoon‐Koo Kang, Zhendong Chen et al. · The Lancet Oncology · 2008 · 5.8K citations

, , +12

Clinical Management of Hepatocellular Carcinoma. Conclusions of the Barcelona-2000 EASL Conference

Jordi Bruix, Morris Sherman, Josep M. Llovet et al. · Journal of Hepatology · 2001 · 4.1K citations

, , +10

Phase II Study of Sorafenib in Patients With Advanced Hepatocellular Carcinoma

Ghassan K. Abou‐Alfa, Lawrence H. Schwartz, Sergio Ricci et al. · Journal of Clinical Oncology · 2006 · 1.2K citations · Full text