Separation of RNA Phosphorothioate Oligonucleotides by HPLC

Bond Order and Charge Localization in Nucleoside Phosphorothioates

Perry A. Frey, R. Douglas Sammons · Science · 1985 · 279 citations

Natural Sciences, Chemistry, Inorganic Chemistry +11

Automated solid-phase synthesis, separation, and stereochemistry of phosphorothioate analogs of oligodeoxyribonucleotides

Wojciech J. Stec, Gerald Zon, William Egan · Journal of the American Chemical Society · 1984 · 275 citations

Natural Sciences, Chemistry, Bioorthogonal Chemistry +10

Phosphorothioation of DNA in bacteria by dnd genes

Lianrong Wang, Shi Chen, Tiegang Xu et al. · Nature Chemical Biology · 2007 · 272 citations

Life Sciences, Microbiology, Molecular Biology +8

Effects of phosphorothioate capping on antivense oligonucleotide stability, hybridization and antiviral efficacy versus herpes simplex virus infection

Glenn D. Hoke, Kenneth Draper, Susan M. Freier et al. · Nucleic Acids Research · 1991 · 248 citations · Full text

Medicine, Infectious Diseases, Pharmacology +13

Evidence for two active sites in the spliceosome provided by stereochemistry of pre-mRNA splicing

Melissa J. Moore, Phillip A. Sharp · Nature · 1993 · 245 citations

Life Sciences, Genetics, Molecular Biology +10