ICU Care at the End of Life

Efficacy and Safety of Recombinant Human Activated Protein C for Severe Sepsis

Gordon R. Bernard, Jean‐Louis Vincent, Pierre‐François Laterre et al. · New England Journal of Medicine · 2001 · 6.1K citations · Full text

Medicine, Pharmacology, Pharmacotherapy +13

Effect of Treatment With Low Doses of Hydrocortisone and Fludrocortisone on Mortality in Patients With Septic Shock

Djillali Annane · JAMA · 2002 · 3.1K citations

Veterinary Medicine, Infectious Diseases, Critical Care Pharmacology +9

A Multicomponent Intervention to Prevent Delirium in Hospitalized Older Patients

Sharon K. Inouye, Sidney T. Bogardus, Peter Charpentier et al. · New England Journal of Medicine · 1999 · 2.9K citations · Full text

Medicine, Geriatric Medicine, Gerontological Nursing +16

A controlled trial to improve care for seriously ill hospitalized patients. The study to understand prognoses and preferences for outcomes and risks of treatments (SUPPORT). The SUPPORT Principal Investigators

Alfred F. Connors, Neal V. Dawson, Norman A. Desbiens et al. · JAMA · 1995 · 2.8K citations

Nursing, Internal Medicine, End-of-life Care +16

A Controlled Trial to Improve Care for Seriously III Hospitalized Patients

Alfred F. Connors · JAMA · 1995 · 2.3K citations

Health Professions, Internal Medicine, Palliative Care +11