Absence of pressure overload induced myocardial hypertrophy after conditional inactivation of Gαq/Gα11 in cardiomyocytes

Prognostic Implications of Echocardiographically Determined Left Ventricular Mass in the Framingham Heart Study

Daniel Levy, Robert J. Garrison, Daniel D. Savage et al. · New England Journal of Medicine · 1990 · 5.7K citations · Full text

Medicine, Cardiology, Internal Medicine +17

Efficient in vivo manipulation of mouse genomic sequences at the zygote stage.

Merja Lakso, José G. Pichel, James Gorman et al. · Proceedings of the National Academy of Sciences · 1996 · 1.1K citations · Full text

Life Sciences, Genetics, Molecular Genetics +15

Transgenic Gαq overexpression induces cardiac contractile failure in mice

Drew D. D’Angelo, Yoshihito Sakata, John N. Lorenz et al. · Proceedings of the National Academy of Sciences · 1997 · 634 citations · Full text

Life Sciences, Cardiology, Physiology +15

Defective platelet activation in Gαq-deficient mice

Stefan Offermanns, Christopher F. Toombs, Yi-Hui Hu et al. · Nature · 1997 · 562 citations

Medicine, Genetics, Hematology +12

Targeting the Receptor-G _q Interface to Inhibit in Vivo Pressure Overload Myocardial Hypertrophy

Shahab A. Akhter, Louis M. Luttrell, Howard A. Rockman et al. · Science · 1998 · 456 citations

Medicine, Cardiology, Pharmacology +17