A Clonal Subpopulation of <i>Leptospira interrogans</i> Sensu Stricto Is the Major Cause of Leptospirosis Outbreaks in Brazil

Abstract

Leptospira is a highly diverse genus comprising many species and serogroups in Brazil as well as all over the world. However, a study by arbitrarily primed PCR of 44 leptospiral strains isolated from humans during three different outbreaks in Brazilian urban centers reveals that 43 of 44 isolates exhibit very similar fingerprints. Analysis of these isolates indicates that they belong to a clonal subpopulation of Leptospira interrogans sensu stricto.