Concepedia

Relationship between inflammation and infliximab pharmacokinetics in rheumatoid arthritis

David Ternant, Émilie Ducourau, Aleth Perdriger, Anca Corondan, Benoît Le Goff, Valérie Devauchelle‐Pensec, Elisabeth Solau‐Gervais, Hervé Watier, Philippe Goupille, Gilles Paintaud,

British Journal of Clinical Pharmacology · 2013 · 80 citations · 21 references

DOIFull text

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Abstract

The influence of methotrexate and inflammation on infliximab clearance suggests that individual adjustment of infliximab doses according to disease activity may be useful in RA.

References

21

Therapeutic efficacy of multiple intravenous infusions of anti-tumor necrosis factor ? monoclonal antibody combined with low-dose weekly methotrexate in rheumatoid arthritis

Ravinder N. Maini, Ferdinand C. Breedveld, Joachim R. Kalden et al. · Arthritis & Rheumatism · 1998 · 1.6K citations

Development and validation of the european league against rheumatism response criteria for rheumatoid arthritis: Comparison with the preliminary american college of rheumatology and the world health organization/international league against rheumatism criteria

Anke M. van Gestel, M.L.L. Prevoo, Martin A. van't Hof et al. · Arthritis & Rheumatism · 1996 · 1.6K citations

General Pharmacokinetic Model for Drugs Exhibiting Target-Mediated Drug Disposition

Donald E. Mager, William J. Jusko · Journal of Pharmacokinetics and Pharmacodynamics · 2001 · 571 citations

Development of antiinfliximab antibodies and relationship to clinical response in patients with rheumatoid arthritis

Marijn Vis, Willem F. Lems, Alexandre E. Voskuyl et al. · Arthritis & Rheumatism · 2006 · 468 citations

Computing normalised prediction distribution errors to evaluate nonlinear mixed-effect models: The npde add-on package for R

Emmanuelle Comets, Karl Brendel, France Mentré · Computer Methods and Programs in Biomedicine · 2008 · 437 citations · Full text

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