Karl Brendel

Computing normalised prediction distribution errors to evaluate nonlinear mixed-effect models: The npde add-on package for R

Emmanuelle Comets, Karl Brendel, France Mentré · Computer Methods and Programs in Biomedicine · 2008 · 437 citations · Full text

Engineering, Data Science, Predictive Analytics +6

Metrics for External Model Evaluation with an Application to the Population Pharmacokinetics of Gliclazide

Karl Brendel, Emmanuelle Comets, Céline M. Laffont et al. · Pharmaceutical Research · 2006 · 295 citations · Full text

External Model Evaluation, Pharmacokinetic Modeling, Drug Discovery +9

Evaluation of different tests based on observations for external model evaluation of population analyses

Karl Brendel, Emmanuelle Comets, Céline M. Laffont et al. · Journal of Pharmacokinetics and Pharmacodynamics · 2009 · 84 citations · Full text

External Model Evaluation, Population Science, Population Analyses +9

Absence of association between MDR1 genetic polymorphisms, indinavir pharmacokinetics and response to highly active antiretroviral therapy

Céline Verstuyft, Fabienne Marcellin, Laurence Morand‐Joubert et al. · AIDS · 2005 · 43 citations

First-in-human phase I study of oral S49076, a unique MET/AXL/FGFR inhibitor, in advanced solid tumours

Jordi Rodón, Sophie Postel‐Vinay, Antoine Hollebecque et al. · European Journal of Cancer · 2017 · 30 citations

Medicine, Metronomic Therapy, Pharmacology +11