Concepedia

Drug Absorption Limited by P-Glycoprotein-Mediated Secretory Drug Transport in Human Intestinal Epithelial Caco-2 Cell Layers

Janice Hunter, Barry H. Hirst, Nicholas L. Simmons

Pharmaceutical Research · 1993 · 221 citations · 24 references

DOI

Concepts

References

24

Characterization of the Human Colon Carcinoma Cell Line (Caco-2) as a Model System for Intestinal Epithelial Permeability

Ismael J. Hidalgo, Thomas J. Raub, Ronald T. Borchardt · Gastroenterology · 1989 · 2.2K citations

, , +14

Correlation between oral drug absorption in humans and apparent drug permeability coefficients in human intestinal epithelial (Caco-2) cells

Per Artursson, Johan Karlsson · Biochemical and Biophysical Research Communications · 1991 · 1.9K citations

, , +16

Enterocyte-like differentiation and polarization of the human colon carcinoma cell line Caco-2 in culture

M. Pinto · HAL (Le Centre pour la Communication Scientifique Directe) · 1983 · 1.8K citations · Full text

, , +7

Structural model of ATP-binding proteing associated with cystic fibrosis, multidrug resistance and bacterial transport

Stephen C. Hyde, Paul Emsley, Michael J. Hartshorn et al. · Nature · 1990 · 1.1K citations

, , +13

Expression of the multidrug resistance gene product (P-glycoprotein) in human normal and tumor tissues.

Carlos Cordon‐Cardo, James P. O’Brien, João Paulo Boccia et al. · Journal of Histochemistry & Cytochemistry · 1990 · 1.1K citations

, , +14