Complete molecular remissions induced by patient-specific vaccination plus granulocyte–monocyte colony-stimulating factor against lymphoma

Vaccination with irradiated tumor cells engineered to secrete murine granulocyte-macrophage colony-stimulating factor stimulates potent, specific, and long-lasting anti-tumor immunity.

Glen Dranoff, Elizabeth M. Jaffee, A Lazenby et al. · Proceedings of the National Academy of Sciences · 1993 · 2.8K citations · Full text

Vaccination, Irradiated Cells, Radiation Oncology +15

Vaccination of patients with B–cell lymphoma using autologous antigen–pulsed dendritic cells

Frank J. Hsu, Claudia Benike, Francesco Fagnoni et al. · Nature Medicine · 1996 · 1.8K citations · Full text

Vaccinology, Vaccination, Lymphoid Neoplasia +12

Immunologic and therapeutic evaluation of a synthetic peptide vaccine for the treatment of patients with metastatic melanoma

Steven A. Rosenberg, James Chih‐Hsin Yang, Douglas J. Schwartzentruber et al. · Nature Medicine · 1998 · 1.8K citations

Vaccination, Therapeutic Evaluation, Melanoma +10

Induction of Immune Responses in Patients with B-Cell Lymphoma against the Surface-Immunoglobulin Idiotype Expressed by Their Tumors

Larry W. Kwak, Michael J. Campbell, Debra K. Czerwinski et al. · New England Journal of Medicine · 1992 · 544 citations

Tumor-Specific Idiotype Vaccines in the Treatment of Patients With B-Cell Lymphoma — Long-Term Results of a Clinical Trial

Frank J. Hsu, Clemens B. Caspar, Debra K. Czerwinski et al. · Blood · 1997 · 453 citations · Full text