Gene transfer in the RPE65 null mutation dog: relationship between construct volume, visual behavior and electroretinographic (ERG) results

Gene therapy restores vision in a canine model of childhood blindness

Gregory M. Acland, Jharna Ray, Qí Zhāng et al. · Nature Genetics · 2001 · 1.2K citations

Medicine, Ophthalmology, Vision Science +16

Rpe65 is necessary for production of 11-cis-vitamin A in the retinal visual cycle

T. Michael Redmond, Shirley Yu, Eric Lee et al. · Nature Genetics · 1998 · 930 citations

Medicine, Ophthalmology, Vision Science +10

Molecular cloning and expression of RPE65, a novel retinal pigment epithelium-specific microsomal protein that is post-transcriptionally regulated in vitro

Christian Hamel, Ekaterini Tsilou, Bruce A. Pfeffer et al. · Journal of Biological Chemistry · 1993 · 335 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +12

New views on RPE65 deficiency: the rod system is the source of vision in a mouse model of Leber congenital amaurosis

Mathias W. Seeliger, Christian Grimm, Fredrik Ståhlberg et al. · Nature Genetics · 2001 · 238 citations

Medicine, Ophthalmology, Vision Science +16

Congenital stationary night blindness in the dog: common mutation in the RPE65 gene indicates founder effect.

Geoffrey K. Aguirre, Victoria J. Baldwin, Sue Pearce‐Kelling et al. · PubMed · 1998 · 220 citations · Full text

Medicine, Genetics, Ophthalmology +15