Shirley Yu

Rpe65 is necessary for production of 11-cis-vitamin A in the retinal visual cycle

T. Michael Redmond, Shirley Yu, Eric Lee et al. · Nature Genetics · 1998 · 930 citations

Medicine, Ophthalmology, Vision Science +10

Mutation of key residues of RPE65 abolishes its enzymatic role as isomerohydrolase in the visual cycle

T. Michael Redmond, Eugenia Poliakov, Shirley Yu et al. · Proceedings of the National Academy of Sciences · 2005 · 411 citations · Full text

Life Sciences, Genetics, Ophthalmology +13

Identification, Expression, and Substrate Specificity of a Mammalian β-Carotene 15,15′-Dioxygenase

T. Michael Redmond, Susan Gentleman, Todd Duncan et al. · Journal of Biological Chemistry · 2001 · 281 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +14

Protection of Rpe65-deficient mice identifies rhodopsin as a mediator of light-induced retinal degeneration

Christian Grimm, Andreas Wenzel, Farhad Hafezi et al. · Nature Genetics · 2000 · 279 citations

Medicine, Ophthalmology, Vision Science +14

Identification of beta‐carotene 15,15′‐monooxygenase as a peroxisome proliferator‐activated receptor target gene

Ana Boulanger, Pamela McLemore, Neal G. Copeland et al. · The FASEB Journal · 2003 · 101 citations

Life Sciences, Biochemistry, Molecular Genetics +13