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HEREDITARY HYPERPARATHYROIDISM ASSOCIATED WITH RECURRENT PANCREATITIS

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1958

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Article1 October 1958HEREDITARY HYPERPARATHYROIDISM ASSOCIATED WITH RECURRENT PANCREATITISCHARLES E. JACKSON, M.D., F.A.C.P.CHARLES E. JACKSON, M.D., F.A.C.P.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-49-4-829 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptThe purpose of this paper is to report six and possibly seven cases of hyperparathyroidism in two generations of one family, associated with recurrent pancreatitis in at least two instances. The hyperparathyroidism was proved in two brothers, a maternal uncle and aunt by excision of parathyroid adenomas, and was established in their mother and another uncle by repeated chemical abnormalities. Reports of hereditary pancreatitis by Gross and Comfort1, 2and Comfort and Steinberg8stimulated an investigation of the family of two brothers who had had repeated attacks of pancreatitis. A serum calcium obtained on the mother after an episode of...Bibliography1. GrossComfort JBMW: Chronic pancreatitis, Am. J. Med. 21: 596, 1956. CrossrefMedlineGoogle Scholar2. GrossComfort JBMW: Hereditary pancreatitis: report on two additional families, Gastroenterology 32: 829, 1957. CrossrefMedlineGoogle Scholar3. ComfortSteinberg MWAG: Pedigree of family with hereditary chronic relapsing pancreatitis, Gastroenterology 21: 54, 1952. CrossrefMedlineGoogle Scholar4. Reifenstein EC, in Robert H. William's Textbook of endocrinology, 1955, W. B. Saunders Co., Philadelphia, p. 566. Google Scholar5. Fales FW: Micromethod for determination of serum calcium, J. Biol. Chem. 204: 577, 1953. CrossrefMedlineGoogle Scholar6. BucknerShively BJA: Determination of serum calcium by a chelating method using a spectrophotometer, Am. J. M. Technol. 21: 269, 1955. MedlineGoogle Scholar7. 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St. Goar WT: Gastrointestinal symptoms as a clue to the diagnosis of primary hyperparathyroidism: a review of 45 cases, Ann. Int. Med. 46: 102-118, 1957. LinkGoogle Scholar20. BogdonoffWoodsWhiteEngel MDAHJEFL: Hyperparathyroidism, Am. J. Med. 21: 583, 1956. CrossrefMedlineGoogle Scholar21. BellArnold GOWT: Primary hyperparathyroidism: report of 2 unusual cases, Lahey Clin. Bull. 6: 197, 1950. MedlineGoogle Scholar22. Hellstrom J: Primary hyperparathyroidism: observation in series of 50 cases, Acta endocrinol. 16: 30, 1954. CrossrefMedlineGoogle Scholar23. Searley RH C. P. C. from 1956 American College of Physicians' Meeting to be reported by , from personal communication with Pratt, O. B. Google Scholar24. RogersKeatingMorlockBarker HMFRCGNW: Primary hypertrophy and hyperplasia of parathyroid glands associated with duodenal ulcer; report of additional case with special reference to metabolic, gastrointestinal and vascular manifestations, Arch. Int. Med. 79: 307, 1947. 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Author, Article, and Disclosure InformationAffiliations: Bluffton, Indiana*Received for publication December 30, 1957.†Supported by the Caylor-Nickel Research Foundation.Requests for reprints should be addressed to Charles E. Jackson, M.D., Caylor-Nickel Clinic, 303 South Main Street, Bluffton, Indiana. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byPathology of the Gastrointestinal Tract in Patients with Primary HyperparathyroidismA large extended family with hyperparathyroidism-jaw tumor syndrome due to deletion of the third exon of CDC73: clinical and molecular featuresThe Unforeseen Diagnosis: Hyperparathyroidism-Jaw Tumour Syndrome Case Report and Review of the LiteratureFamilial HyperparathyroidismHyperparathyroidism-Jaw Tumor SyndromeOvarian Granulosa cell Tumor in a Patient with a Pathogenic Variant in the CDC73 Gene (Hyperparathyroidism-Jaw Tumor Syndrome)Evolution of Our Understanding of the Hyperparathyroid Syndromes: A Historical PerspectiveMolecular genetics of syndromic and non-syndromic forms of parathyroid carcinomaManifestations maxillo-buccodentaires des hyperparathyroïdiesFamilial Hyperparathyroidism: Multiple Endocrine Neoplasia Types II and I; Familial Hypocalciuric Hypercalcemia; Hyperparathyroidism-Jaw Tumor SyndromeGenetic Syndromes Associated with Primary HyperparathyroidismTumor Suppressor Gene Mutation in a Patient With a History of Hyperparathyroidism–Jaw Tumor Syndrome and Healed Generalized Osteitis Fibrosa Cystica: A Case Report and Genetic Pathophysiology ReviewHereditary Hyperparathyroidism SyndromesHyperparathyroidism–Jaw Tumor SyndromeHyperparathyroid Genes: Sequences Reveal Answers and QuestionsHereditary pancreatitisThe Parathyroids and the GutHereditary, Familial, and Genetic Disorders of the Pancreas and Pancreatic Disorders in ChildhoodHyperparathyroidism-Jaw Tumor Syndrome: A Case ReportPathogenesis of Chronic Pancreatitis with Special Emphasis on GenesFisiopatologia e trattamento nelle forme familiari dell'Iperparatiroidismo PrimitivoPrimary Hyperparathyroidism and Jaw Tumor Syndrome: A Novel Mutation of the HRPT2 GeneFurther Observations on the Hereditary form of PancreatitisHereditary chronic pancreatitisHereditary chronic pancreatitisDental findings in a family with hyperparathyroidism–jaw tumor syndrome and a novel HRPT2 gene mutationPrimary hyperparathyroidismPancreatitis and hyperparathyroidismParafibromin, product of the hyperparathyroidism-jaw tumor syndrome gene HRPT2, regulates cyclin D1/PRAD1 expressionUterine tumours are a phenotypic manifestation of the hyperparathyroidism-jaw tumour syndromeHyperparathyroidism-jaw tumour syndromeLimited versus radical parathyroidectomy in familial isolated primary hyperparathyroidismPathophysiologic Basis of Exocrine Pancreatic Dysfunction in ChildhoodParathyroid tumorigenesis in association with primary hyperparathyroidismChronic Pancreatitis, Including Pancreatic LithiasisFamilial Isolated HyperparathyroidismChronic pancreatitis: Diagnosis, classification, and new genetic developmentsFamilial Forms of Primary HyperparathyroidismMolecular Genetics of Familial HyperparathyroidismHyperparathyroidism–Jaw Tumor Syndrome: The HRPT2 Locus Is within a 0.7-cM Region on Chromosome 1qA 50 year perspective endocrine neoplasia: clinic to genes and backIs familial hyperparathyroidism a unique disease?Familial hyperparathyroidism associated with jaw fibroma: case report and literature reviewFamilial childhood parathyroid adenomaHEREDITARY PANCREATITISHereditäre PankreatitisNon-infective Acute PancreatitisFamilial Hypocalciuric HypercalcemiaChronic PancreatitisFamilial hyperparathyroidism.Inherited defect in hereditary pancreatitisFamily studies in patients with primary parathyroid hyperplasiaFamilial Hyperparathyroidism Description of a Large Kindred with Physiologic Observations and a Review of the LiteratureRICHARD E. 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JACKSON, M.D., F.A.C.P.Familial HyperparathyroidismNeonatal Familial Primary HyperparathyroidismThe ParathyroidsEndocrine adenomatosis and peptic ulcer in a large kindredCoexistence of Pancreatitis and Hyperparathyroidism Use of the Secretin Test in Evaluation of Pancreatic Function before and after Excision of a Parathyroid AdenomaD. J. KURLANDER, M.D., H. F. RASKIN, M.D., J. B. KIRSNER, M.D., PH.D.The Clinical Value of Routine Serum Calcium AnalysisC. E. BOONSTRA, M.D., F.A.C.P., C. E. JACKSON, M.D., F.A.C.P.Pancreatitis associated with hyperparathyroidismHereditary pancreatitisFurther Experience with Pancreatitis as a Diagnostic Clue to HyperparathyroidismHyperparathyroidism Analysis of Recent Experiences, Clinical Spectrum, and Diagnostic TestsFRANK A. RIDDICK JR., M.D., ERIC REISS, M.D.Die akuten Erkrankungen der Bauchspeicheldrüse, unter besonderer Berücksichtigung der leichteren Formen und ihrer Bedeutung für die ChirurgieHeredity in Gastroenterology: A ReviewThe Pancreas: Current Contributions of Clinical InterestRecurrent Acute Hyperparathyroidism with Severe Gastrointestinal ManifestationsZur Klinik der Kalkstoffwechselstörungen des ErwachsenenaltersPhysiology of pancreatic secretionThe Association of Peptic Ulcer with Hereditary Hyperparathyroidism 1 October 1958Volume 49, Issue 4Page: 829-836KeywordsAdenomasCalciumHyperparathyroidismPancreatitisParathyroid tumors ePublished: 1 December 2008 Issue Published: 1 October 1958 PDF downloadLoading ...

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