The relation between the divergence of sequence and structure in proteins.

The protein data bank: A computer-based archival file for macromolecular structures

F. C. Bernstein, Thomas F. Koetzle, G. J. B. Williams et al. · Journal of Molecular Biology · 1977 · 8.6K citations

Life Sciences, Biochemistry, Bioinformatics +14

The crystal structure of human deoxyhaemoglobin at 1.74 Å resolution

G. Fermi, M. F. Perutz, Boaz Shaanan et al. · Journal of Molecular Biology · 1984 · 765 citations

Life Sciences, Biochemistry, Biology +13

The Protein Data Bank

F. C. Bernstein, Thomas F. Koetzle, G. J. B. Williams et al. · European Journal of Biochemistry · 1977 · 747 citations

Life Sciences, Biochemistry, Bioinformatics +10

Crystal structures of Escherichia coli and Lactobacillus casei dihydrofolate reductase refined at 1.7 A resolution. I. General features and binding of methotrexate.

J.T. Bolin, David J. Filman, David A. Matthews et al. · Journal of Biological Chemistry · 1982 · 745 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +17

How different amino acid sequences determine similar protein structures: The structure and evolutionary dynamics of the globins

Arthur M. Lesk, Cyrus Chothia · Journal of Molecular Biology · 1980 · 709 citations

Life Sciences, Biochemistry, Evolutionary Biology +16