Concepedia

The influence of a newly developed quinolone: Antoflox-acin, on CYP activity in rats

Xiao Xu, Liu Hai-yan, Liu Li, Lin Xie, Xiaodong Liu

European Journal of Drug Metabolism and Pharmacokinetics · 2008 · 10 citations · 8 references

DOI

Concepts

References

8

The karolinska cocktail for phenotyping of five human cytochrome P450 enzymes

Michael L. Christensen · Clinical Pharmacology & Therapeutics · 2003 · 157 citations

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Optimizing drug development: Strategies to assess drug metabolism/transporter interaction potential-toward a consensus

GT Tucker · Clinical Pharmacology & Therapeutics · 2001 · 154 citations

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Combined phenotypic assessment of cytochrome P450 1A2, 2C9, 2C19, 2D6, and 3A, N-acetyltransferase-2, and xanthine oxidase activities with the “Cooperstown 5+1 cocktail”

Siwaporn Chainuvati · Clinical Pharmacology & Therapeutics · 2003 · 143 citations

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Inhibitory potency of quinolone antibacterial agents against cytochrome P450IA2 activity in vivo and in vitro

Uwe Fuhr, E M Anders, G. Mahr et al. · Antimicrobial Agents and Chemotherapy · 1992 · 136 citations · Full text

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Pharmacokinetic and pharmacodynamic assessment of a five‐probe metabolic cocktail for CYPs 1A2, 3A4, 2C9, 2D6 and 2E1

Graham Blakey, J.A. Lockton, John Perrett et al. · British Journal of Clinical Pharmacology · 2003 · 65 citations · Full text

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