Graham Blakey

A Phase I, Randomized, Double-Blind, Placebo-Controlled, Single Ascending Dose, Multiple Dose, and Food Effect Trial of the Safety, Tolerability and Pharmacokinetics of Highly Purified Cannabidiol in Healthy Subjects

Lesley Taylor, Barry E. Gidal, Graham Blakey et al. · CNS Drugs · 2018 · 448 citations · Full text

A Phase 1, Open‐Label, Pharmacokinetic Trial to Investigate Possible Drug‐Drug Interactions Between Clobazam, Stiripentol, or Valproate and Cannabidiol in Healthy Subjects

Gilmour Morrison, Julie C. Crockett, Graham Blakey et al. · Clinical Pharmacology in Drug Development · 2019 · 195 citations · Full text

Quantitative Structure-Pharmacokinetics Relationships: I. Development of a Whole-Body Physiologically Based Model to Characterize Changes in Pharmacokinetics Across a Homologous Series of Barbiturates in the Rat

Graham Blakey, Ivan Nestorov, Philip A. Arundel et al. · Journal of Pharmacokinetics and Biopharmaceutics · 1997 · 86 citations

Pharmacokinetic and pharmacodynamic assessment of a five‐probe metabolic cocktail for CYPs 1A2, 3A4, 2C9, 2D6 and 2E1

Graham Blakey, J.A. Lockton, John Perrett et al. · British Journal of Clinical Pharmacology · 2003 · 65 citations · Full text

Bayesian decision procedures for dose‐escalation based on evidence of undesirable events and therapeutic benefit

John Whitehead, Yinghui Zhou, John Stevens et al. · Statistics in Medicine · 2005 · 40 citations

Bayesian Decision Theory, Therapeutic Benefit, Treatment Effect +17