Concepedia

Very important pharmacogene summary

Laura M. Hodges, Svetlana Markova, Leslie W. Chinn, Jason M. Gow, Deanna L. Kroetz, Teri E. Klein, Russ B. Altman

Pharmacogenetics and Genomics · 2010 · 433 citations · 121 references

DOIFull text

Open access

Concepts

Abstract

Hodges, Laura M.; Markova, Svetlana M.; Chinn, Leslie W.; Gow, Jason M.; Kroetz, Deanna L.; Klein, Teri E.; Altman, Russ B. Author Information

References

121

A haplotype map of the human genome

Nature · 2005 · 5.9K citations · Full text

, , +17

A surface glycoprotein modulating drug permeability in Chinese hamster ovary cell mutants

R. L. Juliano, Victor Ling · Biochimica et Biophysica Acta (BBA) - Biomembranes · 1976 · 3.3K citations

, , +11

Functional polymorphisms of the human multidrug-resistance gene: Multiple sequence variations and correlation of one allele with P-glycoprotein expression and activity <i>in</i> <i>vivo</i>

Sven Hoffmeyer, Oliver Burk, Oliver von Richter et al. · Proceedings of the National Academy of Sciences · 2000 · 2.4K citations

, , +15

Disruption of the mouse mdr1a P-glycoprotein gene leads to a deficiency in the blood-brain barrier and to increased sensitivity to drugs

Alfred H. Schinkel, Jasper Smit, Olaf van Tellingen et al. · Cell · 1994 · 2.3K citations

, , +14

Structure of P-Glycoprotein Reveals a Molecular Basis for Poly-Specific Drug Binding

Stephen G. Aller, Jodie Yu, Andrew B. Ward et al. · Science · 2009 · 1.9K citations · Full text

, , +12