Maternally expressed PGK-Cre transgene as a tool for early and uniform activation of the Cre site-specific recombinase

Deletion of a DNA Polymerase β Gene Segment in T Cells Using Cell Type-Specific Gene Targeting

Hua Gu, Jamey D. Marth, Paul C. Orban et al. · Science · 1994 · 1.4K citations

Life Sciences, Genetics, Molecular Genetics +17

A<i>cre</i>-transgenic mouse strain for the ubiquitous deletion of<i>loxP</i>-flanked gene segments including deletion in germ cells

Frieder Schwenk, Udo Baron, Klaus Rajewsky · Nucleic Acids Research · 1995 · 1.3K citations

Life Sciences, Genetics, Molecular Genetics +15

Site-specific DNA recombination in mammalian cells by the Cre recombinase of bacteriophage P1.

Brian Sauer, Neil C. Henderson · Proceedings of the National Academy of Sciences · 1988 · 1.2K citations · Full text

Life Sciences, Genetics, Molecular Biology +17

Efficient in vivo manipulation of mouse genomic sequences at the zygote stage.

Merja Lakso, José G. Pichel, James Gorman et al. · Proceedings of the National Academy of Sciences · 1996 · 1.1K citations · Full text

Life Sciences, Genetics, Molecular Genetics +15

Independent control of immunoglobulin switch recombination at individual switch regions evidenced through Cre-loxP-mediated gene targeting

Hua Gu, Yong‐Rui Zou, Klaus Rajewsky · Cell · 1993 · 999 citations

Life Sciences, Genetics, Molecular Biology +16