An epithelial serine protease activates the amiloride-sensitive sodium channel

Amiloride-sensitive epithelial Na+ channel is made of three homologous subunits

Cecilia M. Canessa, Laurent Schild, Gary Buell et al. · Nature · 1994 · 2K citations

Natural Sciences, Biochemistry, Biophysics +13

Liddle's syndrome: Heritable human hypertension caused by mutations in the β subunit of the epithelial sodium channel

Richard A. Shimkets, David G. Warnock, Christopher M. Bositis et al. · Cell · 1994 · 1.3K citations

Life Sciences, Genetics, Molecular Genetics +15

Mutations in subunits of the epithelial sodium channel cause salt wasting with hyperkalaemic acidosis, pseudohypoaldosteronism type 1

Su'e Chang, Stefan Gründer, Aaron Hanukoglu et al. · Nature Genetics · 1996 · 814 citations

Medicine, Molecular Genetics, Physiology +15

A glycophospholipid membrane anchor acts as an apical targeting signal in polarized epithelial cells.

Michael P. Lisanti, Ingrid W. Caras, Michael A. Davitz et al. · The Journal of Cell Biology · 1989 · 478 citations · Full text

Life Sciences, Cell Biology, Molecular Biology +14

Cell surface expression of the epithelial Na channel and a mutant causing Liddle syndrome: A quantitative approach

Dmitri Firsov, Laurent Schild, Ivan Gautschi et al. · Proceedings of the National Academy of Sciences · 1996 · 422 citations · Full text

Natural Sciences, Cell Biology, Pharmacology +17