Social cognition dysfunction in adolescents with 22q11.2 deletion syndrome (velo‐cardio‐facial syndrome): relationship with executive functioning and social competence/functioning

Abstract

Performance on social-cognitive tasks of theory of mind indicate evidence of a general underlying dysfunction in 22q11DS that includes executive ability to understand cause and effect, to logically reason about social scenarios and also to inhibit responses to salient, but misleading cues. However, general intellectual ability is closely related to actual social competence suggesting that a generalised intellectual deficit coupled with more specific executive impairments may best explain poor social cognition in 22q11DS.