Anti‐nuclear antibody positivity and the use of certolizumab in inflammatory bowel disease patients who have had arthralgias or lupus‐like reactions from infliximab or adalimumab

Abstract

Nearly all patients experienced relief from their lupus-like symptoms with certolizumab and 2 out of 4 patients reversed their ANA positivity. While future investigation is warranted, patients who have lupus-like reactions from infliximab or adalimumab may benefit from switching to certolizumab.