Hepatic alpha 1-adrenergic receptors show agonist-specific regulation by guanine nucleotides. Loss of nucleotide effect after adrenalectomy.

LIGAND: A versatile computerized approach for characterization of ligand-binding systems

Peter J. Munson, David Rodbard · Analytical Biochemistry · 1980 · 8.5K citations

Life Sciences, Chemistry, Biomolecular Modeling +11

The role of hormone receptors and GTP-regulatory proteins in membrane transduction

Martin Rodbell · Nature · 1980 · 1.8K citations

Life Sciences, Biochemistry, Molecular Biology +16

A ternary complex model explains the agonist-specific binding properties of the adenylate cyclase-coupled beta-adrenergic receptor.

A. De Léan, Jeffrey M. Stadel, Robert J. Lefkowitz · Journal of Biological Chemistry · 1980 · 1.6K citations · Full text

Medicine, Biochemistry, Pharmacology +17

Isolation of an organ specific protein antigen from cell-surface membrane rat liver

David M. Neville · Biochimica et Biophysica Acta (BBA) - Protein Structure · 1968 · 878 citations

Life Sciences, Biochemistry, Molecular Biology +12

The Glucagon-sensitive Adenyl Cyclase System in Plasma Membranes of Rat Liver

Martin Rodbell, Lutz Birnbaumer, Stephen L. Pohl et al. · Journal of Biological Chemistry · 1971 · 812 citations · Full text

Life Sciences, Biochemistry, Cell Biology +10