Multiple-Dose Pharmacokinetics of Clozapine in Patients

Applied Regression Analysis

Technometrics · 2005 · 18.1K citations

Business, Biostatistics, Mathematics +17

The metabolism of 8-chloro-11-(4-methyl-1-piperazinyl)-5H-dibenzo(b,e) (1,4)diazepine (clozapine) in mice, dogs and human subjects.

R. Gauch, W. Michaelis · PubMed · 1971 · 47 citations

Medicine, Pharmacokinetics, Pharmacology +12

Serum concentrations of clozapine determined by nitrogen selective gas chromatography

R. Heipertz, H. Pilz, WALTÊNIO BECKERS · Archives of Toxicology · 1977 · 36 citations

Pharmacy, Pharmaceutical Analysis, Pharmacology +9

[Exchange of aromatically bound halogen for OH- and SCH3-groups in metabolising clozapine in the human organism (author's transl)].

Birgit Stock, Gerhard Spiteller, R. Heipertz · PubMed · 1977 · 22 citations

Medicine, Medicinal Chemistry, Pharmacology +11