The Structure of Sheep Hemoglobins

Abstract

Abstract The amino acid compositions of the tryptic and chymotryptic peptides of the α chain from sheep hemoglobin A and of the chymotryptic peptides of its insoluble tryptic core have been determined. The α-A chain of the sheep was found to be closely similar to the α-A chain of the goat; the only difference observed was the amino acid residue in position 104 (seryl in goat α-A and threonyl in sheep α-A). No indications were obtained for the presence of a second, structurally different, α chain. The limited structural studies of the α chain of sheep hemoglobin C support the previous observations that this α chain is identical with that of sheep hemoglobin A.