European Journal of Biochemistry · 1976 · 22 citations · 34 references
Life SciencesCell BiologyMolecular BiologyGene ExpressionMorphogenesisProtein TranslationLens AnatomyOcular DevelopmentLens BiologyLens PhysiologyMolecular Weight Determination
Messenger RNA has been isolated from rat lens tissue. The mRNA species which codes for the A2 chain of alpha-crystallin, revealed the same extremely high sedimentation value (14S) as the corresponding messenger from calf lens. However, it has been shown that in rat lens the 14-S messenger preparation directs the synthesis of an additional alpha-crystallin chain, designated as alpha-X with an approximate molecular weight of 24000. For comparative purpose crystallin synthesis has also been studied as well in cultured rat lens cells as in the rat lens cell-free system.
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Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4
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