Unliganded T3R, but not its oncogenic variant, v-erbA, suppresses RAR-dependent transactivation by titrating out RXR.

Direct repeats as selective response elements for the thyroid hormone, retinoic acid, and vitamin D3 receptors

Kazuhiko Umesono, Kevin K. Murakami, Catherine C. Thompson et al. · Cell · 1991 · 1.7K citations · Full text

Chromatin, Genetics, Retinoic Acid +5

Nuclear receptor that identifies a novel retinoic acid response pathway

David J. Mangelsdorf, Estelita S. Ong, Jacqueline A. Dyck et al. · Nature · 1990 · 1.5K citations

Signal Transduction, Nuclear Receptor, Signaling Pathway +10

Retinoid X receptor interacts with nuclear receptors in retinoic acid, thyroid hormone and vitamin D3 signalling

Steven A. Kliewer, Kazuhiko Umesono, David J. Mangelsdorf et al. · Nature · 1992 · 1.5K citations · Full text

Developmental Biology, Signal Transduction, Retinoic Acid +7

The c-erb-A gene encodes a thyroid hormone receptor

Cary Weinberger, Catherine C. Thompson, Estelita S. Ong et al. · Nature · 1986 · 1.5K citations

Signal Transduction, Hormonal Receptor, Genetics +6

The c-erb-A protein is a high-affinity receptor for thyroid hormone

Jan Sap, Alberto Múñoz, Klaus Damm et al. · Nature · 1986 · 1.3K citations

Signal Transduction, Biochemistry, Natural Sciences +9