Concepedia

Orphan Nuclear Receptor ERRα Controls Macrophage Metabolic Signaling and A20 Expression to Negatively Regulate TLR-Induced Inflammation

Jae–Min Yuk, Tae Sung Kim, Soo Yeon Kim, Hyemi Lee, Jeongsu Han, Catherine R. Dufour, Jin Kyung Kim, Hyo Sun Jin, Chul‐Su Yang, Ki-Sun Park,

Immunity · 2015 · 135 citations · 30 references

DOI

Concepts

References

30

Succinate is an inflammatory signal that induces IL-1β through HIF-1α

Gillian M. Tannahill, Annie M. Curtis, Juraj Adamik et al. · Nature · 2013 · 4K citations · Full text

, , +12

Modulation of NF‐κB‐dependent transcription and cell survival by the SIRT1 deacetylase

Fan Yeung, Jamie E. Hoberg, C S Ramsey et al. · The EMBO Journal · 2004 · 2.7K citations · Full text

, , +16

Unresponsiveness of MyD88-Deficient Mice to Endotoxin

Taro Kawai, Osamu Adachi, Tomohiko Ogawa et al. · Immunity · 1999 · 2.1K citations · Full text

, , +8

Metabolic control of muscle mitochondrial function and fatty acid oxidation through SIRT1/PGC‐1α

Zachary Gerhart‐Hines, Joseph T. Rodgers, Olivia Bare et al. · The EMBO Journal · 2007 · 1.3K citations · Full text

, , +16

The ubiquitin-modifying enzyme A20 is required for termination of Toll-like receptor responses

David L. Boone, Emre E. Turer, Eric G. Lee et al. · Nature Immunology · 2004 · 1.1K citations

, , +14