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Heterotransplantation of human cancer. III. Chorioallantoic membranes of embryonated eggs.
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1952
Year
Prior X-radiationTumoral PathologyDevelopmental BiologyXenotransplantationChorioallantoic MembranesMedicinePathologyGynecologyChicken Egg EmbryosHuman Embryonic DevelopmentEmbryonic DevelopmentReproductive BiologyPositive HarvestOncologyMalignant DiseaseCancer ResearchTumor BiologyEmbryology
Twenty-eight of 59 different human cancers (47 per cent) successfully survived transplantation to the chorioallantoic membranes of chicken egg embryos. A total of 620 incubated eggs were used. In terms of the 327 eggs whose embryo survived implantation, the positive harvest was 23 per cent, with or without prior x-radiation. Sarcomas survived in about one-quarter of the eggs harvested, glandular carcinomas in one-fifth, and epidermoid carcinomas in one-seventh.