Selective inhibition of NAALADase, which converts NAAG to glutamate, reduces ischemic brain injury

Reversible middle cerebral artery occlusion without craniectomy in rats.

Enrique Zea Longa, Philip R. Weinstein, Shaun W. Carlson et al. · Stroke · 1989 · 7.5K citations · Full text

Medicine, Neuroscience, Surgery +17

Elevation of the Extracellular Concentrations of Glutamate and Aspartate in Rat Hippocampus During Transient Cerebral Ischemia Monitored by Intracerebral Microdialysis

Helene Benveniste, Jørgen Drejer, Arne Schousboe et al. · Journal of Neurochemistry · 1984 · 2.9K citations

Life Sciences, Neurobiology, Neuroscience +14

Hydrolysis of the brain dipeptide N-acetyl-L-aspartyl-L-glutamate. Identification and characterization of a novel N-acetylated alpha-linked acidic dipeptidase activity from rat brain.

Michael B. Robinson, Randy Blakely, RA Couto et al. · Journal of Biological Chemistry · 1987 · 307 citations · Full text

Life Sciences, Neurobiology, Neuroscience +13

<i>N</i>‐Acetylaspartylglutamate Selectively Activates mGluR3 Receptors in Transfected Cells

Barbara Wróblewska, Jarda T. Wroblewski, S. F. Pshenichkin et al. · Journal of Neurochemistry · 1997 · 299 citations

Life Sciences, Neurobiology, Neuroscience +17

Protection against ischaemic neuronal damage by drugs acting on excitatory neurotransmission.

Brian S. Meldrum · PubMed · 1990 · 299 citations

Medicine, Neuroscience, Pharmacology +17