Mitochondrial involvement in the ageing process. Facts and controversies

Sequence and organization of the human mitochondrial genome

Stephen K. Anderson, Alan T. Bankier, B. G. Barrell et al. · Nature · 1981 · 9.7K citations

Medicine, Genetics, Molecular Genetics +12

The Biologic Clock: The Mitochondria?

Denham Harman · Journal of the American Geriatrics Society · 1972 · 2K citations

Life Sciences, Biology, Physiology +17

Normal oxidative damage to mitochondrial and nuclear DNA is extensive.

Christoph Richter, J W Park, B N Ames · Proceedings of the National Academy of Sciences · 1988 · 1.7K citations · Full text

Life Sciences, Genetics, Molecular Biology +17

MITOCHONDRIAL DNA MUTATIONS AS AN IMPORTANT CONTRIBUTOR TO AGEING AND DEGENERATIVE DISEASES

AnthonyW. Linnane, Takayuki Ozawa, S Marzuki et al. · The Lancet · 1989 · 1.2K citations

Life Sciences, Genetics, Molecular Genetics +12

Mitochondrial DNA deletions in human brain: regional variability and increase with advanced age

Marisol Corral‐Debrinski, Terzah M. Horton, Marie T. Lott et al. · Nature Genetics · 1992 · 886 citations

Life Sciences, Genetics, Neuroscience +16