Memory B-cell persistence is independent of persisting immunizing antigen

Inducible Gene Targeting in Mice

Ralf Kühn, Frieder Schwenk, Michel Aguet et al. · Science · 1995 · 1.9K citations · Full text

A<i>cre</i>-transgenic mouse strain for the ubiquitous deletion of<i>loxP</i>-flanked gene segments including deletion in germ cells

Frieder Schwenk, Udo Baron, Klaus Rajewsky · Nucleic Acids Research · 1995 · 1.3K citations

Knockout Mouse, Germ Cell Fate, Transgenic Mouse Models +15

In Vivo Ablation of Surface Immunoglobulin on Mature B Cells by Inducible Gene Targeting Results in Rapid Cell Death

Kong‐Peng Lam, Ralf Kühn, Klaus Rajewsky · Cell · 1997 · 1.1K citations · Full text

Vivo Ablation, Mature B Cells, Apoptosis +8

Persistence of Memory CD8 T Cells in MHC Class I-Deficient Mice

Kaja Murali‐Krishna, Lisa L. Lau, Suryaprakash Sambhara et al. · Science · 1999 · 719 citations

B–cell memory is short-lived in the absence of antigen

David Gray, Helena Skarvall · Nature · 1988 · 428 citations

Adaptive Immune System, Humoral Response, Immunology +7