Concepedia

The Effect of Diabetes and Insulin on Liver Glycogen Synthetase Activation

Alvin H. Gold

Journal of Biological Chemistry · 1970 · 154 citations · 12 references

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Concepts

Abstract

Alloxan diabetes results in a loss of activity of the liver glycogen synthetase-activating system. Insulin treatment of diabetic rats restores glycogen synthetase activation which suggests a direct hormone effect on the synthetase-activating enzyme.

References

12

Rapid Activation-Inactivation of Liver Uridine Diphosphate Glucose-Glycogen Transferase and Phosphorylase by Insulin and Glucagon in Vivo

Jonathan S. Bishop, Joseph Larner · Journal of Biological Chemistry · 1967 · 134 citations · Full text

, , +13

Induced Synthesis of Hepatic Uridine Diphosphate Glucose-Glycogen Glucosyltransferase after Administration of Insulin to Alloxan-diabetic Rats

Donald F. Steiner, Judith King · Journal of Biological Chemistry · 1964 · 119 citations · Full text

, , +16

Studies on UDPG: α-1,4-Glucan α-4-Glucosyltransferase. VII. Conversion of the Enzyme from Glucose-6-phosphate-dependent to Independent Form in Liver<sup>*</sup>

Susumu Hizukuri, Joseph Larner · Biochemistry · 1964 · 117 citations

, , +10

The Role of Glucose, Glucagon and Glucocorticoids in the Regulation of Liver Glycogen Synthesis

Henri De Wulf, H G Hers · European Journal of Biochemistry · 1968 · 111 citations

, , +15

An on-off mechanism for liver glycogen synthetase activity.

H. J. Mersmann, H L Segal · Proceedings of the National Academy of Sciences · 1967 · 102 citations · Full text

, , +12