Vitreous Is a Barrier in Nonviral Gene Transfer by Cationic Lipids and Polymers

A versatile vector for gene and oligonucleotide transfer into cells in culture and in vivo: polyethylenimine.

Otmane Boussif, Frank Lezoualc’h, Maria Antonietta Zanta et al. · Proceedings of the National Academy of Sciences · 1995 · 6.2K citations

Pharmacy, Biotechnology, Pharmaceutics +17

Stable and efficient gene transfer into the retina using an HIV-based lentiviral vector

Hiroyuki Miyoshi, Masayo Takahashi, Fred H. Gage et al. · Proceedings of the National Academy of Sciences · 1997 · 498 citations

Medicine, Neurobiology, Ophthalmology +12

Construction of plasmids that express<i>E.coli β</i>-galactosidase in mammalian cells

Grant R. MacGregor, C. Thomas Caskey · Nucleic Acids Research · 1989 · 459 citations · Full text

Life Sciences, Genetics, Molecular Biology +16

Interactions of polymeric and liposomal gene delivery systems with extracellular glycosaminoglycans: physicochemical and transfection studies

Marika Ruponen, Seppo Ylä‐Herttuala, Arto Urtti · Biochimica et Biophysica Acta (BBA) - Biomembranes · 1999 · 354 citations

Pharmacy, Molecular Pharmaceutics, Pharmaceutics +16

A human retinal pigment epithelial cell line that retains epithelial characteristics after prolonged culture.

Alberta A. Davis, Paul S. Bernstein, Dean Bok et al. · PubMed · 1995 · 248 citations

Life Sciences, Biochemistry, Cell Biology +13