Chemotherapeutic drugs—more really is not better

THE DISTRIBUTION OF SECONDARY GROWTHS IN CANCER OF THE BREAST.

Stephen A. Paget · The Lancet · 1889 · 5.1K citations

Medicine, Cancer Biology, Oncology +12

Transplacental Carcinogenesis by Stilbestrol

Judah Folkman · New England Journal of Medicine · 1971 · 2.6K citations

Pharmacy, Oncology, Toxicology +17

Cancer Treatment by Targeted Drug Delivery to Tumor Vasculature in a Mouse Model

Wadih Arap, Renata Pasqualini, Erkki Ruoslahti · Science · 1998 · 2.1K citations

Pharmacy, Oncology, Pharmacology +17

Antiangiogenic scheduling of chemotherapy improves efficacy against experimental drug-resistant cancer.

Timothy M. Browder, Catherine Butterfield, Birgit M. Kräling et al. · PubMed · 2000 · 1.6K citations

Medicine, Oncology, Pharmacology +16

Metastasis Results from Preexisting Variant Cells Within a Malignant Tumor

Isaiah J. Fidler, Margaret L. Kripke · Science · 1977 · 1.4K citations

Medicine, Cancer Biology, Oncology +17