IN VIVO MR SPECTROSCOPY OF HUMAN DEMENTIA

Apolipoprotein E: high-avidity binding to beta-amyloid and increased frequency of type 4 allele in late-onset familial Alzheimer disease.

Warren J. Strittmatter, Ann M. Saunders, D. E. Schmechel et al. · Proceedings of the National Academy of Sciences · 1993 · 4.3K citations · Full text

Type 4, Genetics, Genetic Epidemiology +18

Association of apolipoprotein E allele ϵ4 with late‐onset familial and sporadic Alzheimer's disease

Ann M. Saunders, Warren J. Strittmatter, D. E. Schmechel et al. · Neurology · 1993 · 3.8K citations · Full text

Evidence for a membrane defect in Alzheimer disease brain.

Roger M. Nitsch, Jan Krzysztof Blusztajn, Anastassios G. Pittas et al. · Proceedings of the National Academy of Sciences · 1992 · 534 citations

Neurochemical Biomarkers, Alzheimer's Disease, Neurology +17

Localized proton NMR spectroscopy in different regions of the human brain <i>in vivo.</i> Relaxation times and concentrations of cerebral metabolites

Jens Frahm, Harald Bruhn, Michael L. Gyngell et al. · Magnetic Resonance in Medicine · 1989 · 520 citations · Full text

Absolute Quantitation of Water and Metabolites in the Human Brain. II. Metabolite Concentrations

Roland Kreis, Thomas Ernst, Brian D. Ross · Journal of Magnetic Resonance Series B · 1993 · 508 citations

Neuroanatomy, Physiology, Forensic Toxicology +9