Insulin Fragments as a Carrier for Peptide Delivery Across the Blood–Brain Barrier

Continuous infusion of nerve growth factor prevents basal forebrain neuronal death after fimbria fornix transection.

Lawrence R. Williams, S Varon, Gregory M. Peterson et al. · Proceedings of the National Academy of Sciences · 1986 · 1.1K citations

Forebrain Neuronal Death, Cell Death, Peripheral Nerve +20

Amelioration of cholinergic neuron atrophy and spatial memory impairment in aged rats by nerve growth factor

Walter Fischer, Klas Wictorin, Anders Björklund et al. · Nature · 1987 · 1K citations

Aging, Brain Function, Neuroanatomy +11

Anti-transferrin receptor antibody and antibody-drug conjugates cross the blood-brain barrier.

Phillip M. Friden, Lee Walus, Gary F. Musso et al. · Proceedings of the National Academy of Sciences · 1991 · 402 citations · Full text

Endothelial Cells, Immunology, Biomedical Engineering +21

Blood-Brain Barrier Penetration and in Vivo Activity of an NGF Conjugate

Phillip M. Friden, Lee Walus, Patricia M. Watson et al. · Science · 1993 · 320 citations

Central Cholinergic Neurons, Cerebral Vascular Regulation, Neuroinflammation +20

A Major Metabolite of Arginine Vasopressin in the Brain Is a Highly Potent Neuropeptide

J. Peter H. Burbach, Gábor L. Kovaćs, D. de Wied et al. · Science · 1983 · 262 citations

Vasopressin Fragment, Synaptic Transmission, Neurotransmitter +18