1976 · 12 citations · 0 references
Natural SciencesChemistryEarth SciencesAir PollutionAtmospheric ChemistryAtmospheric ScienceAtmospheric CompositionAtmospheric Oxidation ProcessesAtmospheric Trace GasesCarbon MonoxideStratospheric ChemistryTropospheric ChemistryChemical DegradationChemical Degradation KineticsChemical Degradation PathwaysLifetimesQuasi-equilibrium ApproximationTropospheric CompositionTropospheric Halogen ChemistryTropospheric Radical Chemistry
Fusion of the E. coli GyrB and GyrA proteins leads to a catalytically active topoisomerase which compensates several phenotypic traits attributed to unconstrained DNA supercoiling in topoisomerase-deficient cells. However, since the fusion protein cannot substitute for topoisomerase II, it may be efficient in intramolecular but not intermolecular DNA passage, resembling the catalytic properties of DNA gyrase.