PubMed · 1996 · 25 citations · 0 references
PharmacyInfectious DiseasesPharmacotherapyImmunopathologyInflammationVirologyAntiviral AgentsAntiviral PharmacologyAntiviral PharmacotherapyAntiviral TherapyInterferon-based TherapyTreatmentAntiviral TherapeuticsGuinea Pig ModelsMarburg Virus DiseaseRibavirin TherapyTumor Necrosis Factor Therapy
The paper presents data on the effects of the drugs desferal, ribavirin and homologous (guinea pig) interferon on the course of experimental Marburg fever. Neither ribavirin nor interferon were effective. A moderate response to desferal was noted. It is suggested that tumor necrosis factor may contribute to development of Marburg hemorrhagic fever.