Curcumin Inhibits Neuronal Loss in the Retina and Elevates Ca ²⁺ /Calmodulin-Dependent Protein Kinase II Activity in Diabetic Rats

Abstract

Curcumin attenuated diabetes-induced apoptosis in retinal neurons by reducing the glutamate level and downregulating CaMKII. Thus, curcumin might be used to prevent neuronal damage in the retina of patients with diabetes mellitus.