Enamine (Ukraine)

Ultra-large library docking for discovering new chemotypes

Jiankun Lyu, Sheng Wang, Trent E. Balius et al. · Nature · 2019 · 947 citations

Targeted Library, Medicine, Natural Sciences +6

An open-source drug discovery platform enables ultra-large virtual screens

Christoph Gorgulla, Andras Boeszoermenyi, Zifu Wang et al. · Nature · 2020 · 612 citations · Full text

Virtual Screening, Hit Identification, Medicine +5

Synthon-based ligand discovery in virtual libraries of over 11 billion compounds

Arman A. Sadybekov, Anastasiia Sadybekov, Yongfeng Liu et al. · Nature · 2021 · 415 citations · Full text

Combinatorial Chemistry, Targeted Library, Medicinal Chemistry +11

Hindered dialkyl ether synthesis with electrogenerated carbocations

Jinbao Xiang, Ming Shang, Yu Kawamata et al. · Nature · 2019 · 382 citations

Engineering, Organic Electrochemistry, Electrosynthesis +5

Virtual discovery of melatonin receptor ligands to modulate circadian rhythms

Reed M. Stein, Hye Jin Kang, John D. McCorvy et al. · Nature · 2020 · 307 citations · Full text

Sleep, Medicinal Chemistry, Signal Transduction +13