Altravax (United States)

Vaccine-Elicited Tier 2 HIV-1 Neutralizing Antibodies Bind to Quaternary Epitopes Involving Glycan-Deficient Patches Proximal to the CD4 Binding Site

Ema T. Crooks, Tommy Tong, Bimal K. Chakrabarti et al. · PLoS Pathogens · 2015 · 145 citations · Full text

Vaccination, Native Env Trimer, Molecular Virology +14

Functional Stability of Unliganded Envelope Glycoprotein Spikes among Isolates of Human Immunodeficiency Virus Type 1 (HIV-1)

Nitish Agrawal, Daniel P. Leaman, Eric Rowcliffe et al. · PLoS ONE · 2011 · 39 citations · Full text

Effects of partially dismantling the CD4 binding site glycan fence of HIV-1 Envelope glycoprotein trimers on neutralizing antibody induction

Ema T. Crooks, Keiko Osawa, Tommy R. Tong et al. · Virology · 2017 · 38 citations · Full text

Human Retrovirus, Immunology, Antiviral Response +7

A Human Antibody to the CD4 Binding Site of gp120 Capable of Highly Potent but Sporadic Cross Clade Neutralization of Primary HIV-1

Johannes S. Gach, Heribert Quendler, Tommy Tong et al. · PLoS ONE · 2013 · 20 citations · Full text

Hiv-1 Resist Neutralization, Systems Biology, Medicine +15

Prime-Boost Immunization of Rabbits with HIV-1 gp120 Elicits Potent Neutralization Activity against a Primary Viral Isolate

Kristin Narayan, Nitish Agrawal, Sean X. Du et al. · PLoS ONE · 2013 · 17 citations · Full text

Primary Viral Isolate, Immunology, Immunodominance +17