Arsenal Biosciences (United States)

TOX transcriptionally and epigenetically programs CD8+ T cell exhaustion

Omar Khan, Josephine R. Giles, Sierra McDonald et al. · Nature · 2019 · 1.5K citations

Transcriptional Regulation, T-regulatory Cell, Gene Expression +3

Developmental Relationships of Four Exhausted CD8+ T Cell Subsets Reveals Underlying Transcriptional and Epigenetic Landscape Control Mechanisms

Jean‐Christophe Beltra, Sasikanth Manne, Mohamed S. Abdel-Hakeem et al. · Immunity · 2020 · 974 citations · Full text

Chromatin, Transcriptional Regulation, Lineage Plasticity +11

Peripheral T cell expansion predicts tumour infiltration and clinical response

Thomas D. Wu, Shravan Madireddi, Patrícia E. de Almeida et al. · Nature · 2020 · 770 citations

Cancer Immunosurveillance, Medicine, T-regulatory Cell +8

In vivo CRISPR screens reveal the landscape of immune evasion pathways across cancer

Juan Dubrot, Peter P. Du, Sarah Kate Lane-Reticker et al. · Nature Immunology · 2022 · 198 citations

Tumor Biology, Immunology, Tumor Immunity +10

PI3K activation allows immune evasion by promoting an inhibitory myeloid tumor microenvironment

Natalie B. Collins, Rose Al Abosy, Brian C. Miller et al. · Journal for ImmunoTherapy of Cancer · 2022 · 112 citations · Full text