Optivia Biotechnology (United States)

Contribution of the organic anion transporter OAT2 to the renal active tubular secretion of creatinine and mechanism for serum creatinine elevations caused by cobicistat

Eve‐Irene Lepist, Xuexiang Zhang, Hao Jia et al. · Kidney International · 2014 · 239 citations · Full text

Discovery of Potent, Selective Multidrug and Toxin Extrusion Transporter 1 (MATE1, SLC47A1) Inhibitors Through Prescription Drug Profiling and Computational Modeling

Matthias Wittwer, Arik A. Zur, Natalia Khuri et al. · Journal of Medicinal Chemistry · 2012 · 141 citations · Full text

Drug Target, Transporter 1, Pharmacotherapy +17

Discovery of Competitive and Noncompetitive Ligands of the Organic Cation Transporter 1 (OCT1; SLC22A1)

Eugene C. Chen, Natalia Khuri, Xiaomin Liang et al. · Journal of Medicinal Chemistry · 2017 · 64 citations · Full text

Fluorescence-based assays for the assessment of drug interaction with the human transporters OATP1B1 and OATP1B3

Dallas Bednarczyk · Analytical Biochemistry · 2010 · 62 citations · Full text

Human Transporters Oatp1b1, Drug Interaction, Biochemistry +8

The Effect of Famotidine, a MATE1-Selective Inhibitor, on the Pharmacokinetics and Pharmacodynamics of Metformin

Jennifer Hibma, Arik A. Zur, Richard A. Castro et al. · Clinical Pharmacokinetics · 2015 · 57 citations · Full text

Pharmacological Study, Biochemistry, Medicine +5