2-Carboxyquinoxalines Kill <i>Mycobacterium tuberculosis</i> through Noncovalent Inhibition of DprE1

João Neres, Ruben C. Hartkoorn, Laurent R. Chiarelli, +26

ACS Chemical Biology

Tuberculosis PreventionBacteriologyMolecular BiologyAntimicrobial ChemotherapyDrug Resistance +19

Aggravation of atherosclerosis by hypertension in a subhuman primate model with coarctation of the aorta.

William Hollander, Irving M. Madoff, John Paddock, +1

Circulation Research

ThrombosisHypertensionVascular DiseaseCardiovascular DiseaseVascular Adaptation +13

Long period fiber grating working in reflection mode as valuable biosensing platform for the detection of drug resistant bacteria

Giuseppe Quero, Simona Zuppolini, M. Consales, +10

Sensors and Actuators B Chemical

Photonic SensorReflection ModeEngineeringBiosensing SystemsMedicine +9

Computational and biological profile of boronic acids for the detection of bacterial serine- and metallo-β-lactamases

Matteo Santucci, Francesca Spyrakis, Simon Cross, +11

Scientific Reports

X-ray Crystallography Deciphers the Activity of Broad-Spectrum Boronic Acid β-Lactamase Inhibitors

Laura Cendron, Antonio Quotadamo, Lorenzo Maso, +6

ACS Medicinal Chemistry Letters

X-ray CrystallographyMolecular BiologyAntimicrobial ChemotherapySerine BlsChemical Biology +22

Virtual screening identifies broad-spectrum β-lactamase inhibitors with activity on clinically relevant serine- and metallo-carbapenemases

Francesca Spyrakis, Matteo Santucci, Lorenzo Maso, +11

Scientific Reports

Comparative mapping of on-targets and off-targets for the discovery of anti-trypanosomatid folate pathway inhibitors

Joanna Panecka-Hofman, Ina Pöhner, Francesca Spyrakis, +9

Biochimica et Biophysica Acta (BBA) - General Subjects

Drug TargetBiochemistryAfrican TrypanosomiasisMedicineRational Drug Design +4

Sleep, Obesity, and Injury Among US Male Career Firefighters

Christopher M. Kaipust, Sara A. Jahnke, Walker S. Carlos Poston, +4

Journal of Occupational and Environmental Medicine

Label-free fiber optic optrode for the detection of class C β-lactamases expressed by drug resistant bacteria

Simona Zuppolini, Giuseppe Quero, M. Consales, +10

Biomedical Optics Express

EngineeringEscherichia ColiFiber OpticsClass C β-LactamasesAntibiotic Resistance +21

Accelerating Drug Discovery Efforts for Trypanosomatidic Infections Using an Integrated Transnational Academic Drug Discovery Platform

Carolina Borsoi Moraes, Gesa Witt, Maria Kuzikov, +39

SLAS DISCOVERY