Galapagos (Netherlands)

Mice deficient in the Rac activator Tiam1 are resistant to Ras-induced skin tumours

Angeliki Malliri, Rob A. van der Kammen, Kristopher Clark et al. · Nature · 2002 · 383 citations

Ras-induced Skin Tumours, Rac Activator Tiam1, Medicine +9

Efficacy and safety of filgotinib, a selective Janus kinase 1 inhibitor, in patients with active ankylosing spondylitis (TORTUGA): results from a randomised, placebo-controlled, phase 2 trial

Désirée van der Heijde, Xenofon Baraliakos, Lianne S. Gensler et al. · The Lancet · 2018 · 251 citations · Full text

Rheumatoid Disorder, Rheumatology, Autoimmune Disease +7

Efficacy and safety of filgotinib, a selective Janus kinase 1 inhibitor, in patients with active psoriatic arthritis (EQUATOR): results from a randomised, placebo-controlled, phase 2 trial

Philip J. Mease, Laura C. Coates, Philip Helliwell et al. · The Lancet · 2018 · 202 citations · Full text

The Orphan G Protein–Coupled Receptor 3 Modulates Amyloid-Beta Peptide Generation in Neurons

Amantha Thathiah, Kurt Spittaels, Marcel Hoffmann et al. · Science · 2009 · 193 citations

Development of a Gut-on-a-Chip Model for High Throughput Disease Modeling and Drug Discovery

Claudia Beaurivage, Elena Naumovska, Yee Chang et al. · International Journal of Molecular Sciences · 2019 · 175 citations · Full text