Génomique Fonctionnelle des Tumeurs Solides

Exome sequencing of hepatocellular carcinomas identifies new mutational signatures and potential therapeutic targets

Kornelius Schulze, Sandrine Imbeaud, Éric Letouzé et al. · Nature Genetics · 2015 · 1.8K citations · Full text

Potential Therapeutic Targets, Exome Sequencing, Medicine +9

Integrated analysis of somatic mutations and focal copy-number changes identifies key genes and pathways in hepatocellular carcinoma

Cécile Guichard, Giuliana Amaddeo, Sandrine Imbeaud et al. · Nature Genetics · 2012 · 1.4K citations · Full text

Engineering, Somatic Mutations, Somatic Variant +7

Toward understanding and exploiting tumor heterogeneity

Ash A. Alizadeh, Victoria Aranda, Alberto Bardelli et al. · Nature Medicine · 2015 · 749 citations · Full text

Tumor Heterogeneity, Cancer Genomics, Medicine +5

MicroRNA profiling in hepatocellular tumors is associated with clinical features and oncogene/tumor suppressor gene mutations

Yannick Ladeiro, Gabrielle Couchy, Charles Balabaud et al. · Hepatology · 2008 · 676 citations · Full text

High frequency of telomerase reverse-transcriptase promoter somatic mutations in hepatocellular carcinoma and preneoplastic lesions

Jean‐Charles Nault, Maxime Mallet, Camilla Pilati et al. · Nature Communications · 2013 · 648 citations · Full text