Siamab Therapeutics (United States)

Novel anti-Sialyl-Tn monoclonal antibodies and antibody-drug conjugates demonstrate tumor specificity and anti-tumor activity

Jillian M. Prendergast, Ana Paula da Silva, David A. Eavarone et al. · mAbs · 2017 · 84 citations · Full text

Immunology, Immunotherapeutics, Immunotherapy +18

Humanized anti-Sialyl-Tn antibodies for the treatment of ovarian carcinoma

David A. Eavarone, Linah Al-Alem, Alexey A. Lugovskoy et al. · PLoS ONE · 2018 · 51 citations · Full text

Malignant Disease, Medicine, Pharmacology +15

Treatment of ovarian cancer by targeting the tumor stem cell-associated carbohydrate antigen, Sialyl-Thomsen-nouveau

Kristen Starbuck, Linah Al-Alem, David A. Eavarone et al. · Oncotarget · 2018 · 41 citations · Full text

The novel anti-androgen candidate galeterone targets deubiquitinating enzymes, USP12 and USP46, to control prostate cancer growth and survival

Urszula L. McClurg, Mahsa Azizyan, Daniel T. Dransfield et al. · Oncotarget · 2018 · 31 citations · Full text

Androgen Receptor, Urology, Endocrine-related Cancer +11

Sialyl-Tn serves as a potential therapeutic target for ovarian cancer

Linah Al-Alem, Jillian M. Prendergast, Justin Clark et al. · Journal of Ovarian Research · 2024 · 15 citations · Full text