Patrys (Germany)

A new tumor-specific variant of GRP78 as target for antibody-based therapy

Nicole Rauschert, Stephanie Brändlein, Elisabeth Holzinger et al. · Laboratory Investigation · 2008 · 128 citations · Full text

New Tumor-specific Variant, Immunology, Antibody Screening +9

GRP78-directed immunotherapy in relapsed or refractory multiple myeloma - results from a phase 1 trial with the monoclonal immunoglobulin M antibody PAT-SM6

Leo Rasche, Johannes Duell, Inês C. Castro et al. · Haematologica · 2015 · 101 citations · Full text

Expression and glycoengineering of functionally active heteromultimeric IgM in plants

Andreas Loos, Clemens Grünwald‐Gruber, Friedrich Altmann et al. · Proceedings of the National Academy of Sciences · 2014 · 79 citations · Full text

Plant Physiology, Molecular Pharming, Glycobiology +19

The Natural Human IgM Antibody PAT-SM6 Induces Apoptosis in Primary Human Multiple Myeloma Cells by Targeting Heat Shock Protein GRP78

Leo Rasche, Johannes Duell, Charlotte Morgner et al. · PLoS ONE · 2013 · 68 citations · Full text

Malignant Blood Disorder, Apoptosis, Immunology +12

High level expression of functional human IgMs in human PER.C6® cells

Anna Tchoudakova, Frank Hensel, Alec Murillo et al. · mAbs · 2009 · 61 citations · Full text